Best X Builds

AI hiring in San Francisco

49 AI and ML jobs in San Francisco posted on X by a founder, hiring manager, or teammate. Location is whatever the original post said.

49 roles · updated 2026-10-29

Engineer

Engineering

Paradev

Engineer, in the office in San Francisco five days a week. Show work you have shipped. Posted by a cofounder.

San Francisco@FlyaKiet

Google DeepMind

Research engineer on Gemini large scale pretraining. London or Mountain View. Posted by a research engineer on the team.

London / Mountain View@zacharynado

OpenAI

Developer experience engineer with the cyber team. San Francisco. Posted by the head of developer experience.

San Francisco@romainhuet

GTM Intern

Content / Media

Photon

GTM intern, two seats, on-site in San Francisco. Email juliec@mail.grokbot.com. Posted by the CMO.

San Francisco@0xJuliechen

Marketing

Content / Media

Photon

Full-time marketing, on-site in San Francisco. Same post. Posted by the CMO.

San Francisco@0xJuliechen

DevRel

Engineering

Photon

Full-time developer relations, on-site in San Francisco. Same post. Posted by the CMO.

San Francisco@0xJuliechen

aion

Senior product design, hybrid, across San Francisco, New York, London, and beyond. Posted by the company.

San Francisco / New York / London@aionxyz

aion

Senior design engineer on the same hiring post. Posted by the company.

San Francisco / New York / London@aionxyz

Human Archive

Robot learning intern in the San Francisco office. Posted by the founder.

San Francisco, CA@babugi28

OpenAI

Two senior seats on the plugins developer platform. San Francisco, relocation provided. Posted by someone on the team.

San Francisco, CA@mxstbr

OpenAI

Android engineer on the same plugins platform. San Francisco, relocation provided. Posted by someone on the team.

San Francisco, CA@mxstbr

Prime Intellect

Agent harnesses, cloud agents, self-improving loops, sandboxes, evals. SF, in person. Posted by someone on the team.

San Francisco, United States@kevinjosethomas

Engineer

Engineering

Aside

Memory, computer use, compaction, agent loop. $160k to $300k plus equity. SF, in person. Posted by the CEO.

San Francisco, United States@hyojun_at

Robocurve

Frontier robotics evals. $170k-$300k, $5k referrals. San Francisco, in person. Posted by the co-founder.

San Francisco, United States@chooi_jeq

Andera

AI agents for audit. $37M Series A. San Francisco, on-site. Posted by a teammate at Hack the North.

San Francisco, United States@natashajchen

Andera

Product engineering lead for AI audit agents. San Francisco, on-site. Posted by a teammate.

San Francisco, United States@natashajchen

Andera

Infrastructure for AI audit agents. San Francisco, on-site. Posted by a teammate.

San Francisco, United States@natashajchen

Lead AI Engineer

Engineering

Andera

Lead AI engineer for audit agents. San Francisco, on-site. Posted by a teammate.

San Francisco, United States@natashajchen

Product Engineer

Engineering

Andera

Product engineer for AI audit agents. San Francisco, on-site. Posted by a teammate.

San Francisco, United States@natashajchen

LearnVector

Design engineer, in-person Mountain View. Andrew Ng's learning product. Posted by the hiring person on the team.

Mountain View, CA@dimapyanov

Proximal

Build the applied research function and sit with customers. North Beach, SF. Posted by a co-founder.

San Francisco, CA@MatternJustus

ASAPP

Enterprise contact-center AI. Ship, not just roadmaps. Posted by someone on the team.

New York / Mountain View@Aishwaryaradhya

Encode

Lab engagement and AI policy in San Francisco, with regular DC trips. Founder post. Email sneha@encodeai.org by Sep 4.

San Francisco, CA@SnehaRevanur

Anthropic

Scientific judgment and ops for drug discovery work. NYC and SF. Posted by someone on the team.

San Francisco / New York, NY@nc_frey

Tessl

DevRel for agent skills and context. San Francisco. Posted by the company.

San Francisco, US@tessl_io

Profound

Applied AI for an enterprise marketing harness. SF and NYC, no remote. Posted by the CTO.

San Francisco / New York, NY@dbabbs

Engineer

Engineering

Merge

Engineers in SF and NYC. Connective layer for AI in product and workforce. Posted by the cofounder.

San Francisco / New York@GilFeig

Mintlify

Applied AI engineer. Hiring across San Francisco and New York.

San Francisco / New York, USA@mintlify

Inferact

Head of Engineering on the vLLM inference stack. Up to $280k, SF. a16z Build list.

San Francisco, US@katieschwartz

Munari

a16z Speedrun. Reliability infra so robots work in the real world, not just the lab. On-site SF.

San Francisco, US@katieschwartz

OpenAI

Lead senior full-stack engineers building AI-native learning in ChatGPT. a16z Build list.

San Francisco, US@katieschwartz

OpenEvidence

Elite engineer on special projects with the founders. Sequoia partner Shaun Maguire posting. Medical AI used by most US doctors.

San Francisco / Miami, US@shaunmmaguire

Tenera

a16z Speedrun-backed. Predict how users react to software before you ship. Own agent infra, backend, and frontend.

San Francisco, US@katieschwartz

Town

Personal AI assistant after a $55M Series A. Rethink email, calendar, and contacts. Posted by a16z New Media.

San Francisco / New York, US@thedanigrant

Phylo

AI biomedical discovery lab. Work with pharma and biotech. Up to $275k. a16z Build list.

South San Francisco, US@katieschwartz

Product Engineer

Engineering

Runta

Safer execution environment for agents. $20M seed. SDK, CLI, APIs, DX. Up to $200k. a16z Build list.

San Francisco, US@katieschwartz

Brix AI

AI Product Manager Intern role at an HF0-incubated AI company building proactive AI workforce agents.

Palo Alto / Shanghai / Remote@PeihongD

VC-backed startups (via Clera)

Exceptional engineers for SF and NYC startups. Base up to $300k plus meaningful equity.

SF & NYC@_sebastianscott

Ryze

Build autonomous marketing and creative systems. Above-market pay. Remote OK.

Remote (SF preferred)@irabukht